A significant obstacle to treating cancer is multidrug resistance (MDR), which is the capacity of cancerous cells to develop resistance to both traditional and cutting-edge chemotherapeutic treatments.Following the initial discovery that cellular pumps reliant on ATP were the root of chemotherapy resistance, more research has revealed the involveme
Scientific and economic life flourished in Andalusia during the reign of Prince Abdul Rahman II.This development and economic prosperity affected all aspects of the life of the Andalusian people, and this was reflected in the intellectual and cultural aspects and the journey in seeking knowledge.The Lounge Set journey in seeking knowledge was one o
Delusion is the most difficult problem in psychopathology.In the existing definitions of delusion there is no clear indication of the discriminant that enables us to reliably distinguish it from other psychopathologic phenomena.This paper proposes an approach to examine delusion as semiotic object that has a symbolic nature.The paper accentuates th
A concrete element when kept under sustained load presents progressive strain over time, associated to the creep.In reinforced concrete columns, such deformations cause the stress increase in the steel bars of the reinforcement and may induce the material to undergo Balm the yielding phenomenon.The pioneering formulations about the creep effect, de
BACKGROUND:Human adult adipose-derived stem cells (hADSCs) have become the most promising cell source for regenerative medicine.However the prolonged ex vivo expansion periods required to obtain the necessary therapeutic dose promotes progressive senescence, with the concomitant reduction of their therapeutic potential.AIM AND SCOPE:A better unders